We study the development of the fruit fly, Drosophila melanogaster. We are interested in the mechanisms of formation of gene expression patterns in Drosophila development, and in animal development in general. We are most interested in systems-level properties of the patterns, such as fine-tuning, robustness, and size-dependent properties. We use fruit fly genetics, computational and theoretical modeling, and imaging of live and fixed tissues to approach these problems.
Focus Areas - Biological Engineering. Engineering Principles of Cell-Cell Communication. Tissue Patterning. Feedback Control of Developing Tissues.